产品描述
概述
L-Amino Acid Oxidase is an oligomeric glycoprotein composed of unequal amounts of two different approximately 70 kDa subunits. Three electrophoretically different isozymes occur as different combinations of the two subunits. there are approximately two moles of FAD per mole of holo-enzyme. L-amino acid oxidase catalyzes the oxidative deamination of a number of L-amino acids. The enzyme is absolutely specific for L-isomers. Our product is prepared according to Wellner and Meister, JBC, 235, 2013, (1960) to the point just prior to crystallization.
应用
生化研究。能够抑制由ADP和胶原所引起的血小板聚集。具有细胞毒性,能诱导细胞凋亡。能抑制大肠杆菌,金黄色葡萄球菌和痢疾杆菌的生长,杀死肿瘤细胞以及诱导血小板聚集,这些活性能被过氧化氢酶所抑制。本品仅供科研使用。
促进天然氨基酸的氧化。
属性
保存缓冲液 |
加入甲苯的水溶液
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生物来源 |
东部菱背响尾蛇毒液
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活性 |
Activity ≥4 U/mg protein
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单位定义 |
一个单位在 25°C,pH 7.6下每分钟氧化 1 μmol L -亮氨酸。
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