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Order NO. C600037
重组人IFN-α2b,酵母表达
英文名 Recombinant Human Interferon-alpha2b, Ye
相关类别 细胞因子 储存 冷冻(-20℃)
分子量 Approximately 19.3 kDa, a single polypeptide chain containing 165 amino acids.    
   
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C600037-0100 100 UG 咨询
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产品描述

概述

IFN-αs are proteins secreted by leukocyte. They are mainly involved in innate immune response against viral infection. The IFN-α family has 13 subtypes and 23 different variants. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-alpha subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 98 % by SDS-PAGE and HPLC analyses.
Source Saccharomyces cerevisiae
Biological Activity Fully biologically active when compared to standard. The specific activity determined by an anti-viral assay is no less than 1.6 × 108 IU/mg.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Endotoxin Less than 0.1 EU/μg of rHuIFN-α2b, Yeast as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE
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