在线客服
网站反馈
网站指南
我的会员中心
中文
我的草稿
我的购物车
Order NO. C650034
小鼠抗MSH6单克隆抗体
英文名 Anti-MSH6 mouse monoclonal antibody
相关类别 IVD抗体原料 最新产品 储存 冷冻（-20℃） 参照组件的存储要求
编 号 规格 库存 目录价（￥） 您的价格（￥） 数 量
C650034-0100 100UG 预计7日内发货 待询价 待询价
加入购物车
C650034-0500 500UG 预计7日内发货 待询价 待询价
加入购物车
产品描述

应用

immunohistochemistry：anti-MSH6 mouse monoclonal antibody.human gastric cancer tissue and colorectal cancer tissue.

组分

1 mg/ml

适用样本

Human

属性

Background This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013]
Product name Anti-MSH6 mouse monoclonal antibody
Description Mouse monoclonal antibody to MSH6
Host species Mouse
Tested applications IHC
Reactivity Human
Immunogen Recombinant protein. The exact sequence is proprietary.
Clone number SG201136m
Isotype IgG2a
Purification Protein A/G affinity column
Uniprot ID P52701
相关文档
Sample Application

  • IHC image of MSH6 staining in a formalin fixed, paraffin embedded human gastric cancer tissue (left) and colorectal cancer tissue (right). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer for 20 minutes. The tissue section was then incubated with mouse anti-MSH6（C650034）antibody overnight at 4℃.HRP-conjugated goat anti-mouse IgG was used as secondary antibody. (Original magnification: 100×).