
Order NO. C650034
小鼠抗MSH6单克隆抗体
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
C650034-0100 | 100UG | 预计7日内发货 |
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C650034-0500 | 500UG | 预计7日内发货 |
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产品描述
应用
immunohistochemistry:anti-MSH6 mouse monoclonal antibody.human gastric cancer tissue and colorectal cancer tissue.
组分
1 mg/ml
适用样本
Human
属性
Background | This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] |
Product name | Anti-MSH6 mouse monoclonal antibody |
Description | Mouse monoclonal antibody to MSH6 |
Host species | Mouse |
Tested applications | IHC |
Reactivity | Human |
Immunogen | Recombinant protein. The exact sequence is proprietary. |
Clone number | SG201136m |
Isotype | IgG2a |
Purification | Protein A/G affinity column |
Uniprot ID | P52701 |