小鼠抗Caldesmon单克隆抗体,Anti-Caldesmon mouse monoclonal antibody 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C650046

小鼠抗Caldesmon单克隆抗体

英文名	Anti-Caldesmon mouse monoclonal antibody
相关类别	IVD抗体原料	储存	冷冻（-20℃）参照组件的存储要求

产品描述

应用

immunohistochemistry：anti-Caldesmon mouse monoclonal antibody.human esophgus cancer tissue and vermiform appendix tissue.

1 mg/ml

Human

Background	This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Product name	Anti-Caldesmon mouse monoclonal antibody
Description	Mouse monoclonal antibody to Caldesmon
Host species	Mouse
Tested applications	IHC
Reactivity	Human
Immunogen	Recombinant protein. The exact sequence is proprietary.
Clone number	SG200146m
Isotype	IgG2b
Purification	Protein A/G affinity column
Uniprot ID	Q05682

相关文档

Sample Application

IHC image of Caldesmon staining in a formalin fixed, paraffin embedded human esophgus cancer tissue (left) and vermiform appendix tissue (right). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer for 20 minutes. The tissue section was then incubated with mouse anti-Caldesmon（C650046）antibody overnight at 4℃.HRP-conjugated goat anti-mouse IgG was used as secondary antibody. (Original magnification: 100×).