Order NO. C650061
小鼠抗AR 单克隆抗体
| 英文名 | Anti-AR mouse monoclonal antibody | ||
| 相关类别 | IVD抗体原料 | 储存 | 冷冻（-20℃） 参照组件的存储要求 |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| C650061-0100 | 100UG | 预计7日内发货 |
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| C650061-0500 | 500UG | 预计7日内发货 |
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产品描述
应用
immunohistochemistry：anti-AR mouse monoclonal antibody
组分
1 mg/ml
适用样本
Human
属性
| Background | The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. |
| Product name | Anti-AR mouse monoclonal antibody |
| Description | Mouse monoclonal antibody to AR |
| Host species | Mouse |
| Tested applications | IHC |
| Reactivity | Human |
| Immunogen | Recombinant protein. The exact sequence is proprietary. |
| Clone number | SG200076m |
| Isotype | IgG2b |
| Purification | Protein A/G affinity column |
| Uniprot ID | P10275 |
相关文档
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Sample Application
