Order NO. D120404
兔抗CDKN1B多克隆抗体
| 英文名 | Anti-CDKN1B rabbit polyclonal antibody | ||
| 别名 | cyclin dependent kinase inhibitor 1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human, Mouse |
| 克隆类型 | rabbit polyclonal | 抗原 | CDKN1B |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D120404-0025 | 25 ul | 现货 |
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| D120404-0100 | 100 ul | 现货 |
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| D120404-0200 | 200 ul | 现货 |
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产品描述
概述
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P46527 |
| 靶点基因 ID | 1027 |
| 靶点全称 | cyclin dependent kinase inhibitor 1B |
| 靶点别名 | KIP1; MEN4; CDKN4; MEN1B; P27KIP1 |
| 靶点研究领域 | Epigenetics and Nuclear Signaling, Cancer |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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