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| 编 号 | 规格 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D121410-0025 | 25 ul | 现货 | 待询价 | 待询价 |
|
| D121410-0100 | 100 ul | 现货 | 待询价 | 待询价 |
|
| D121410-0200 | 200 ul | 现货 | 待询价 | 待询价 |
|
概述
This gene encodes vitamin D3 receptor, which is a member of the nuclear hormone receptor superfamily of ligand-inducible transcription factors. This receptor also functions as a receptor for the secondary bile acid, lithocholic acid. Downstream targets of vitamin D3 receptor are principally involved in mineral metabolism, though this receptor regulates a variety of other metabolic pathways, such as those involved in immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P11473 |
| 靶点基因 ID | 7421 |
| 靶点全称 | vitamin D receptor |
| 靶点别名 | NR1I1; PPP1R163 |
| 靶点研究领域 | Signal Transduction, Epigenetics and Nuclear Signaling |
| 亚型 | Immunogen-specific rabbit IgG |
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