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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D122046-0025 | 25 ul | 现货 | 待询价 | 待询价 |
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D122046-0100 | 100 ul | 现货 | 待询价 | 待询价 |
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D122046-0200 | 200 ul | 现货 | 待询价 | 待询价 |
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概述
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. The use of alternative promoters results in multiple transcript variants encoding the same protein. The protein is primarily expressed in the hematopoietic system. The use by some variants of an alternate promoter in an upstream long terminal repeat (LTR) results in placenta-specific expression.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | P14784 |
靶点基因 ID | 3560 |
靶点全称 | interleukin 2 receptor subunit beta |
靶点别名 | CD122; IMD63; IL15RB; P70-75 |
靶点研究领域 | Signal Transduction, Immunology, Stem Cells |
亚型 | Immunogen-specific rabbit IgG |

