人CFB重组蛋白（hFc tag C-Terminus）,Human CFB Recombinant protein (hFc tag C-Terminus) 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

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Order NO. D145224

人CFB重组蛋白（hFc tag C-Terminus）

英文名	Human CFB Recombinant protein (hFc tag C-Terminus)
别名	complement factor B; BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14
相关类别	抗原	储存	冷冻（-20℃）
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编号	包装	库存	目录价（￥）	您的价格（￥）	数量
D145224-0010	10 UG	预计5日内发货			暂不支持线上订购
D145224-0050	50 UG	预计5日内发货			暂不支持线上订购
D145224-0100	100 UG	预计5日内发货			暂不支持线上订购

产品描述

概述

Fusion protein corresponding to a region derived from 26-764 amino acids of Human CFB

属性

Full name:	complement factor B
Synonyms:	BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14
Swissprot:	P00751
Purity:	>95%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	HEK293
Tags:	hFc tag C-Terminus
Species:	Human
Molecular mass:	The protein has a predicted molecular weight of 109.2 kDa after removal of the signal peptide. The apparent molecular weight of CFB-hFc is approximately 100-130 kDa due to glycosylation.
Research areas:	Immunology
Background:	This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

相关文档

Sample Application

Purified Human CFB Recombinant Protein (Catalog number: D145224) was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

质量控制相关文件

质量报告 (COA)