Order NO. D151204
兔抗PTEN（phospho-Ser370）多克隆抗体
| 英文名 | Anti-PTEN (phospho-Ser370) rabbit polyclonal antibody | ||
| 别名 | phosphatase and tensin homolog; BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human Mouse Rat |
| 克隆类型 | rabbit polyclonal | 抗原 | PTEN |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D151204-0050 | 50 ul | 预计5日内发货 |
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| D151204-0100 | 100 ul | 预计7日内发货 |
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| D151204-0200 | 200 ul | 预计7日内发货 |
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产品描述
概述
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
应用
免疫印迹（WB），免疫组织化学（IHC），免疫荧光（IF）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | P60484 |
| 靶点基因 ID | 5728 |
| 靶点全称 | phosphatase and tensin homolog |
| 靶点别名 | BZS; DEC; CWS1; GLM2; MHAM; TEP1; MMAC1; PTEN1; 10q23del |
| 靶点研究领域 | Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Metabolism |
| 亚型 | Immunogen-specific rabbit IgG |
相关文档
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Sample Application
