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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D151226-0050 | 50 ul | 预计5日内发货 | 待询价 | 待询价 |
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D151226-0100 | 100 ul | 预计7日内发货 | 待询价 | 待询价 |
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D151226-0200 | 200 ul | 预计7日内发货 | 待询价 | 待询价 |
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概述
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Several transcript variants encoding distinct isoforms have been identified for this gene. It is possible that distinct isoforms of beta chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. Distinct isoforms of this chain have different expression patterns.
应用
免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | Q9UQM7/Q13554/Q13557 |
靶点基因 ID | 815/816/817 |
靶点全称 | calcium/calmodulin dependent protein kinase II alpha/beta/delta |
靶点别名 | CAMKA; MRD53; MRT63; CaMKIIalpha; CaMKIINalpha; CAM2; CAMK2; CAMKB; MRD54; CaMKIIbeta; CAMKD |
靶点研究领域 | Cardiovascular, Signal Transduction, Neuroscience |
亚型 | Immunogen-specific rabbit IgG |

