Order NO. D151295
产品描述
概述
This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. The receptor consists of an extracellular domain composed of five immunoglobulin-like domains, one transmembrane region, and a cytoplasmic kinase domain split into two parts by a kinase-insert domain. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor.
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P36888
|
靶点基因 ID |
2322
|
靶点全称 |
fms-related tyrosine kinase 3
|
靶点别名 |
FLK2; STK1; CD135; FLK-2
|
靶点研究领域 |
Signal Transduction, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|