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Order NO. D151363
兔抗GAB2(phospho-Ser623)多克隆抗体
英文名 Anti-GAB2 (phospho-Ser623) rabbit polyclonal antibody
别名 GRB2-associated binding protein 2; GAB2
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human Mouse
克隆类型 rabbit polyclonal 抗原 GAB2
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D151363-0050 50 ul 预计5日内发货
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D151363-0100 100 ul 预计7日内发货
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D151363-0200 200 ul 预计7日内发货
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产品描述

概述

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

应用

免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q9UQC2
靶点基因 ID 9846
靶点全称 GRB2-associated binding protein 2
靶点别名 GAB2
靶点研究领域 Signal Transduction, Neuroscience
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using D151363(GAB2(Phospho-Ser623) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane 1-4: 293 cells, Hela cells and HepG2 cells, lane1 is treated with antigen-specific peptide lysates, Primary antibody: D151363(GAB2(Phospho-Ser623) Antibody) at dilution 1/500 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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