Order NO. D151488
产品描述
概述
This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function.
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P00519
|
靶点基因 ID |
25
|
靶点全称 |
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
靶点别名 |
ABL; JTK7; p150; c-ABL; v-abl; c-ABL1; bcr/abl
|
靶点研究领域 |
Signal Transduction, Epigenetics and Nuclear Signaling, Cancer
|
亚型 |
Immunogen-specific rabbit IgG
|