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Order NO. D151675
兔抗RB1(Ab-608)多克隆抗体
英文名 Anti-RB1 (Ab-608) rabbit polyclonal antibody
别名 retinoblastoma 1; RB; pRb; OSRC; pp110; p105-Rb; PPP1R130
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
克隆类型 rabbit polyclonal 抗原 RB1
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D151675-0050 50 ul 预计5日内发货
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D151675-0100 100 ul 预计7日内发货
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D151675-0200 200 ul 预计7日内发货
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产品描述

概述

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

应用

免疫印迹(WB)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P06400
靶点基因 ID 5925
靶点全称 retinoblastoma 1
靶点别名 RB; pRb; OSRC; pp110; p105-Rb; PPP1R130
靶点研究领域 Epigenetics and Nuclear Signaling, Cancer
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane: Jurkat cells treated with PMA (125ng/ml, 30mins) lysate, Primary antibody: D151675(RB1(Ab-608) Antibody) at dilution 1/500 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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