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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D153236-0025 | 25 ul | 现货 | 待询价 | 待询价 |
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D153236-0050 | 50 ul | 预计5日内发货 | 待询价 | 待询价 |
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D153236-0100 | 100 ul | 预计7日内发货 | 待询价 | 待询价 |
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D153236-0200 | 200 ul | 预计7日内发货 | 待询价 | 待询价 |
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概述
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.
应用
免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | Q8WYR1 |
靶点基因 ID | 23533 |
靶点全称 | phosphoinositide-3-kinase, regulatory subunit 5 |
靶点别名 | p101; FOAP-2; P101-PI3K; F730038I15Rik |
靶点研究领域 | Signal Transduction |
亚型 | Immunogen-specific rabbit IgG |

