兔抗MAP3K5(Ab-83)多克隆抗体,Anti-MAP3K5 (Ab-83) rabbit polyclonal antibody 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. D153570

兔抗MAP3K5(Ab-83)多克隆抗体

英文名	Anti-MAP3K5 (Ab-83) rabbit polyclonal antibody
别名	mitogen-activated protein kinase kinase kinase 5; ASK1; MEKK5; MAPKKK5
相关类别	一抗	储存	冷冻（-20℃）
宿主	Rabbit	反应种属	Human
克隆类型	rabbit polyclonal	抗原	MAP3K5
在线咨询

编号	规格	库存	目录价（￥）	您的价格（￥）	数量
D153570-0050	50 ul	预计5日内发货	待询价	待询价
D153570-0100	100 ul	预计5日内发货	待询价	待询价
D153570-0200	200 ul	预计5日内发货	待询价	待询价

产品描述

概述

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.

应用

免疫印迹（WB），免疫组织化学（IHC），免疫荧光（IF）

属性

保存缓冲液	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件	2-8°C
靶点 Uniprot 登记号	Q99683
靶点基因 ID	4217
靶点全称	mitogen-activated protein kinase kinase kinase 5
靶点别名	ASK1; MEKK5; MAPKKK5
靶点研究领域	Cancer, Cardiovascular
亚型	Immunogen-specific rabbit IgG

相关文档

Sample Application

The image is immunofluorescence of Hela cells using D153570(MAP3K5(Ab-83) Antibody) at dilution 1/100.
The image on the left is immunohistochemistry of paraffin-embedded Human breast carcinoma tissue using D153570(MAP3K5(Ab-83) Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane: MDA-MB-435 cell lysate, Primary antibody: D153570(MAP3K5(Ab-83) Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute