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Order NO. D160009
兔抗CASP3 (active)多克隆抗体
英文名 Anti-CASP3 (active) rabbit polyclonal antibody
别名 caspase 3, apoptosis-related cysteine peptidase; CPP32, SCA-1, CPP32B
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
克隆类型 rabbit polyclonal 抗原 CASP3
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D160009-0025 25 ul 现货
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D160009-0100 100 ul 现货
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D160009-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 P42574
靶点基因 ID 836
靶点全称 caspase 3
靶点别名 CPP32; SCA-1; CPP32B
靶点研究领域 Cancer,Cell Biology,Neuroscience
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-4: HL60 apoptotic cells after 48 hours of starvation, Hela apoptotic cells after 48 hours of starvation, Jurkat apoptotic cells after 48 hours of starvation, A549 cell lysates, Primary antibody: D160009(CASP3 (active) Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute
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