Order NO. D160480
产品描述
概述
This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
亚型 |
Immunogen-specific rabbit IgG
|
靶点研究领域 |
Epigenetics and Nuclear Signaling, Cardiovascular, Signal Transduction
|
靶点别名 |
HD2, RPD3, YAF1
|
靶点全称 |
histone deacetylase 2
|
靶点基因 ID |
3066
|
靶点 Uniprot 登记号 |
Q92769
|
运输条件 |
2-8°C
|
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|