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Order NO. D160723
兔抗RAD51多克隆抗体
英文名 Anti-RAD51 rabbit polyclonal antibody
别名 RECA, BRCC5, MRMV2, HRAD51, RAD51A, HsRad51, HsT16930
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 RAD51
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D160723-0025 25 ul 现货
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D160723-0100 100 ul 现货
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D160723-0200 200 ul 现货
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产品描述

概述

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.

应用

酶联免疫吸附测定(ELISA),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q06609
靶点基因 ID 5888
靶点全称 RAD51 recombinase
靶点别名 RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930
靶点研究领域 Epigenetics and Nuclear Signaling
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D160723(RAD51 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using D160723(RAD51 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

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