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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D161024-0025 | 25 ul | 现货 | 待询价 | 待询价 |
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D161024-0100 | 100 ul | 现货 | 待询价 | 待询价 |
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D161024-0200 | 200 ul | 现货 | 待询价 | 待询价 |
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概述
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | Q00653 |
靶点基因 ID | 4791 |
靶点全称 | nuclear factor kappa B subunit 2 |
靶点别名 | p52; p100; H2TF1; LYT10; CVID10; LYT-10; NF-kB2; p49/p100 |
靶点研究领域 | Signal Transduction, Epigenetics and Nuclear Signaling |
亚型 | Immunogen-specific rabbit IgG |

