Order NO. D161524
产品描述
概述
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P28908
|
靶点基因 ID |
943
|
靶点全称 |
tumor necrosis factor receptor superfamily, member 8
|
靶点别名 |
CD30; Ki-1; D1S166E
|
靶点研究领域 |
Cancer, Immunology
|
亚型 |
Immunogen-specific rabbit IgG
|