Order NO. D161571
产品描述
概述
Capillary morphogenesis protein 1 (CMG1), also known as intraflagellar transport protein 74 (ITP74) or coiled-coil domain-containing protein 2 (CCDC2), is a 600 amino acid human homologue of IFT-71, a complex B protein supporting intraflagellar transport (IFT) in Chlamydomonas. CMG1 localizes to the cytoplasmic vesicle and is highly expressed in adult and fetal kidney and testis, with lower levels of expression in adult heart, placenta, lung, liver and pancreas, and in fetal heart, lung and liver. CMG1 has been suggested to have a role in the primary cilia of HUVEC, and it also functions as a transcriptional regulator of cyclin D2 in spermatocyte-derived cells.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q96LB3
|
靶点基因 ID |
80173
|
靶点全称 |
intraflagellar transport 74 homolog (Chlamydomonas)
|
靶点别名 |
CMG1; CCDC2; CMG-1
|
靶点研究领域 |
Cardiovascular
|
亚型 |
Immunogen-specific rabbit IgG
|