Order NO. D162371
产品描述
概述
LIN-41, also called tripartite motif-containing 71 (TRIM71), which was first identified in Caenorhabditis elegans, is responsible for the timing of cell fate determination. By encoding microRNAs (miRNAs), the heterochronic genes let-7 and lin-4 downregulate the gene encoding LIN-41. The miRNAs bind to six complementary sites on the 3' untranslated region (UTR) of the LIN-41 gene. This downregulation positively regulates the timing of the expression of LIN-29, an adult specification transcription factor.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q2Q1W2
|
靶点基因 ID |
131405
|
靶点全称 |
tripartite motif containing 71, E3 ubiquitin protein ligase
|
靶点别名 |
LIN41; LIN-41
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靶点研究领域 |
Epigenetics and Nuclear Signaling
|
亚型 |
Immunogen-specific rabbit IgG
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