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Order NO. D162975
兔抗TGFB1多克隆抗体
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D162975-0025 | 25 ul | 现货 |
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| D162975-0100 | 100 ul | 现货 |
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| D162975-0200 | 200 ul | 现货 |
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属性
| Background: | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. |
| Applications: | ELISA, WB |
| Name of antibody: | TGFB1 |
| Immunogen: | Synthetic peptide of human TGFB1 |
| Full name: | transforming growth factor beta 1 |
| Synonyms: | CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1 |
| SwissProt: | P01137 |
| ELISA Recommended dilution: | 5000-10000 |
| WB Predicted band size: | 44 kDa |
| WB Positive control: | Mouse skin tissue lysate |
| WB Recommended dilution: | 1000-5000 |
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