Order NO. D190734
产品描述
概述
This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues.
应用
免疫印迹(WB)
属性
保存缓冲液 |
-20°C, PBS(pH 7.4)containing 0.02% sodium azide and 50% glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
Q9H9Z2
|
靶点基因 ID |
79727
|
靶点全称 |
lin-28 homolog A
|
靶点别名 |
CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A
|
靶点研究领域 |
Epigenetics and Nuclear Signaling
|
亚型 |
IgG2a
|