Order NO. D195476
小鼠抗CTNNB1 (mutated S45F)单克隆抗体
| 英文名 | Anti-CTNNB1 (mutated S45F) mouse monoclonal antibody | ||
| 别名 | catenin beta 1; EVR7; CTNNB; MRD19; NEDSDV; armadillo | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Mouse | 反应种属 | Recognizes S45F mutant, but not wild-type Human CTNNB1 |
| 标记物 | Unconjugate | 克隆类型 | mouse monoclonal |
| 抗原 | CTNNB1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D195476-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. |
| Applications: | ELISA, WB, IF |
| Name of antibody: | CTNNB1 (mutated S45F) |
| Immunogen: | A synthetic peptide from the internal region of human CTNNB1 which includes the mutation of S45F |
| Full name: | catenin beta 1 |
| Synonyms: | EVR7; CTNNB; MRD19; NEDSDV; armadillo |
| SwissProt: | P35222 |
| ELISA Recommended dilution: | 1000-5000 |
| WB Predicted band size: | 85 kDa |
| WB Positive control: | Purified His-tagged CTNNB1 (mutated S45F) protein |
| WB Recommended dilution: | 500-1000 |
| IF Recommended dilution: | 50-100 |
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