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编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D220954-0025 | 25 ul | 现货 | 待询价 | 待询价 |
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D220954-0100 | 100 ul | 现货 | 待询价 | 待询价 |
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D220954-0200 | 200 ul | 现货 | 待询价 | 待询价 |
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概述
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
运输条件 | 2-8°C |
靶点 Uniprot 登记号 | P48740 |
靶点基因 ID | 5648 |
靶点全称 | mannan binding lectin serine peptidase 1 |
靶点别名 | 3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1 |
靶点研究领域 | Immunology |
亚型 | Immunogen-specific rabbit IgG |

