Order NO. D223953
产品描述
概述
The LIN proteins regulate an intercellular signaling process that induces formation of the hermaphrodite vulva in C. elegans by acting to prevent the activation of a receptor tyrosine kinase/Ras signaling pathway. LIN37 is a 246 amino acid protein that is a mammalian homolog of the C. elegans Lin-37 protein. LIN37 functions as a component of the DREAM complex (also known as the LINC complex), which is comprised of several proteins, all of which work in concert to repress cell cycle-dependent genes. LIN37 is encoded by a gene located on human chromosome 19q13.2.
应用
酶联免疫吸附测定(ELISA),免疫组织化学(IHC)
属性
亚型 |
Immunogen-specific rabbit IgG
|
靶点研究领域 |
Epigenetics and Nuclear Signaling
|
靶点别名 |
F25965; lin-37; ZK418.4
|
靶点全称 |
lin-37 DREAM MuvB core complex component
|
靶点基因 ID |
55957
|
靶点 Uniprot 登记号 |
Q96GY3
|
运输条件 |
2-8°C
|
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|