Order NO. D261541
产品描述
概述
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
应用
酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)
属性
保存缓冲液 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
|
运输条件 |
2-8°C
|
靶点 Uniprot 登记号 |
P30260
|
靶点基因 ID |
996
|
靶点全称 |
cell division cycle 27
|
靶点别名 |
APC3; HNUC; NUC2; ANAPC3; CDC27Hs; D0S1430E; D17S978E
|
靶点研究领域 |
Cancer, Cell Biology
|
亚型 |
Immunogen-specific rabbit IgG
|