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| 编 号 | 规格 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D262438-0025 | 25 ul | 现货 | 待询价 | 待询价 |
|
| D262438-0100 | 100 ul | 现货 | 待询价 | 待询价 |
|
| D262438-0200 | 200 ul | 现货 | 待询价 | 待询价 |
|
概述
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
应用
酶联免疫吸附测定（ELISA），免疫组织化学（IHC）
属性
| 保存缓冲液 | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 运输条件 | 2-8°C |
| 靶点 Uniprot 登记号 | Q9H3M7 |
| 靶点基因 ID | 10628 |
| 靶点全称 | thioredoxin interacting protein |
| 靶点别名 | THIF; VDUP1; HHCPA78; EST01027 |
| 靶点研究领域 | Metabolism, Epigenetics and Nuclear Signaling, Cancer, Cell Biology |
| 亚型 | Immunogen-specific rabbit IgG |
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