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Order NO. D262619
兔抗SLC7A11多克隆抗体
英文名 Anti-SLC7A11 rabbit polyclonal antibody
别名 xCT; CCBR1
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse
克隆类型 rabbit polyclonal 抗原 SLC7A11
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D262619-0025 25 ul 现货
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D262619-0100 100 ul 现货
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D262619-0200 200 ul 现货
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产品描述

概述

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

应用

酶联免疫吸附测定(ELISA),免疫印迹(WB),免疫组织化学(IHC)

属性

保存缓冲液 -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
运输条件 2-8°C
靶点 Uniprot 登记号 Q9UPY5
靶点基因 ID 23657
靶点全称 solute carrier family 7 member 11
靶点别名 xCT; CCBR1
靶点研究领域 Metabolism, Cell Biology
亚型 Immunogen-specific rabbit IgG
相关文档
Sample Application

  • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using D262619(SLC7A11 Antibody) at dilution 1/65, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using D262619(SLC7A11 Antibody) at dilution 1/65, on the right is treated with synthetic peptide. (Original magnification: ×200)


  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela and 293T cell lysates, Primary antibody: D262619(SLC7A11 Antibody) at dilution 1/1200, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 30 seconds
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