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Order NO. D263014
兔抗GHRL多克隆抗体
英文名 Anti-GHRL rabbit polyclonal antibody
别名 ghrelin and obestatin prepropeptide; MTLRP
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human, Mouse, Rat
标记物 Unconjugate 克隆类型 rabbit polyclonal
抗原 GHRL    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D263014-0025 25 ul 现货
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D263014-0100 100 ul 现货
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D263014-0200 200 ul 现货
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属性

Background: This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression. [provided by RefSeq, Nov 2014] (The background information is obtained from official databases and does not represent the product information.)
Applications: ELISA, WB, IHC
Name of antibody: GHRL
Immunogen: Synthetic peptide of human GHRL
Full name: ghrelin and obestatin prepropeptide
Synonyms: MTLRP
SwissProt: Q9UBU3
ELISA Recommended dilution: 5000-10000
IHC positive control: Human stomach
IHC Recommend dilution: 50-200
WB Predicted band size: 13 kDa
WB Positive control: Hela, 293T cell lysates
WB Recommended dilution: 500-2000
相关文档
Sample Application

  • The image is immunohistochemistry of paraffin-embedded Human stomach tissue using D263014(GHRL Antibody) at dilution 1/50. (Original magnification: ×200)

  • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela, 293T cell lysates, Primary antibody: D263014(GHRL Antibody) at dilution 1/1300, Secondary antibody: D110058(HRP-conjugated Goat anti rabbit IgG) at 1/5000 dilution, Exposure time: 90 seconds
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