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Order NO. D290018
兔抗ACLY (phospho-Thr447/Ser451)单克隆抗体
英文名 Anti-ACLY (phospho-Thr447/Ser451) rabbit monoclonal antibody
别名 ATP citrate lyase; ACL; ATPCL; CLATP
相关类别 一抗 储存 冷冻(-20℃)
宿主 Rabbit 反应种属 Human
标记物 Unconjugate 克隆类型 rabbit monoclonal
抗原 ACLY (phospho-Thr447/Ser451)    
   
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
D290018-0050 50 ul 预计5日内发货
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D290018-0100 100 ul 预计5日内发货
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属性

Background: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
Applications: WB
Name of antibody: ACLY (phospho-Thr447/Ser451)
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Thr447/Ser451 of human ACLY
Full name: ATP citrate lyase
Synonyms: ACL; ATPCL; CLATP
SwissProt: P53396
WB Predicted band size: 121 kDa
WB Positive control: K562 lysate
WB Recommended dilution: 500-2000
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Sample Application

  • Gel: 6%SDS-PAGE, Lysate: 30 μg, Lane: K562 lysate, Primary antibody: D290018(ACLY (phospho-Thr447/Ser451) Antibody) at dilution 1/1000, Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes
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