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Order NO. D290018
兔抗ACLY (phospho-Thr447/Ser451)单克隆抗体
编 号 | 规格 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D290018-0050 | 50 ul | 预计5日内发货 | 待询价 | 待询价 |
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D290018-0100 | 100 ul | 预计5日内发货 | 待询价 | 待询价 |
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属性
Background: | ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014] |
Applications: | WB |
Name of antibody: | ACLY (phospho-Thr447/Ser451) |
Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding Thr447/Ser451 of human ACLY |
Full name: | ATP citrate lyase |
Synonyms: | ACL; ATPCL; CLATP |
SwissProt: | P53396 |
WB Predicted band size: | 121 kDa |
WB Positive control: | K562 lysate |
WB Recommended dilution: | 500-2000 |
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