Order NO. D290694
兔抗HSD17B1单克隆抗体
| 英文名 | Anti-HSD17B1 rabbit monoclonal antibody | ||
| 别名 | hydroxysteroid 17-beta dehydrogenase 1; E2DH; HSD17; EDHB17; EDH17B2; SDR28C1; 17-beta-HSD; 20-alpha-HSD | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | HSD17B1 | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D290694-0050 | 50 ul | 预计5日内发货 |
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| D290694-0100 | 100 ul | 预计5日内发货 |
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属性
| Background: | This gene encodes a member of the 17beta-hydroxysteroid dehydrogenase family of short-chain dehydrogenases/reductases. It has a dual function in estrogen activation and androgen inactivation and plays a major role in establishing the estrogen E2 concentration gradient between serum and peripheral tissues. The encoded protein catalyzes the last step in estrogen activation, using NADPH to convert estrogens E1 and E2 and androgens like 4-androstenedione, to testosterone. It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site, and a narrow, hydrophobic C-terminal domain with a steroid substrate binding site. This gene is expressed primarily in the placenta and ovarian granulosa cells, and to a lesser extent, in the endometrium, adipose tissue, and prostate. Polymorphisms in this gene have been linked to breast and prostate cancer. A pseudogene of this gene has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
| Applications: | WB |
| Name of antibody: | HSD17B1 |
| Immunogen: | Synthetic peptide of human HSD17B1 |
| Full name: | hydroxysteroid 17-beta dehydrogenase 1 |
| Synonyms: | E2DH; HSD17; EDHB17; EDH17B2; SDR28C1; 17-beta-HSD; 20-alpha-HSD |
| SwissProt: | P14061 |
| WB Predicted band size: | 35 kDa |
| WB Positive control: | Human placenta lysate |
| WB Recommended dilution: | 500-2000 |
相关文档
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Sample Application
