Order NO. D291077
兔抗NUP98单克隆抗体
| 英文名 | Anti-NUP98 rabbit monoclonal antibody | ||
| 别名 | nucleoporin 98 and 96 precursor; ADIR2; NUP96; NUP196; Nup98-96 | ||
| 相关类别 | 一抗 | 储存 | 冷冻（-20℃） |
| 宿主 | Rabbit | 反应种属 | Human |
| 标记物 | Unconjugate | 克隆类型 | rabbit monoclonal |
| 抗原 | NUP98 | ||
|
|||
| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D291077-0050 | 50 ul | 预计5日内发货 |
|
|
|
| D291077-0100 | 100 ul | 预计5日内发货 |
|
|
|
属性
| Background: | Nuclear pore complexes (NPCs) regulate the transport of macromolecules between the nucleus and cytoplasm, and are composed of many polypeptide subunits, many of which belong to the nucleoporin family. This gene belongs to the nucleoporin gene family and encodes a 186 kDa precursor protein that undergoes autoproteolytic cleavage to generate a 98 kDa nucleoporin and 96 kDa nucleoporin. The 98 kDa nucleoporin contains a Gly-Leu-Phe-Gly (GLGF) repeat domain and participates in many cellular processes, including nuclear import, nuclear export, mitotic progression, and regulation of gene expression. The 96 kDa nucleoporin is a scaffold component of the NPC. Proteolytic cleavage is important for targeting of the proteins to the NPC. Translocations between this gene and many other partner genes have been observed in different leukemias. Rearrangements typically result in chimeras with the N-terminal GLGF domain of this gene to the C-terminus of the partner gene. Alternative splicing results in multiple transcript variants encoding different isoforms, at least two of which are proteolytically processed. Some variants lack the region that encodes the 96 kDa nucleoporin. [provided by RefSeq, Feb 2016] |
| Applications: | WB |
| Name of antibody: | NUP98 |
| Immunogen: | Fusion protein of human NUP98 |
| Full name: | nucleoporin 98 and 96 precursor |
| Synonyms: | ADIR2; NUP96; NUP196; Nup98-96 |
| SwissProt: | P52948 |
| WB Predicted band size: | 198 kDa |
| WB Positive control: | Hela, A549, HL-60 lysates |
| WB Recommended dilution: | 500-2000 |
相关文档
|
||||
Sample Application
