Order NO. D622399
GADD45B抗原（重组蛋白）
| 英文名 | GADD45B Antigen (Recombinant Protein) | ||
| 别名 | MYD118; GADD45BETA | ||
| 相关类别 | 抗原 | 储存 | 冷冻（-20℃） |
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| D622399-0001 | 1 MG | 预计30日内发货 |
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| D622399-0100 | 100 UG | 预计30日内发货 |
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产品描述
概述
Fusion protein corresponding to a region derived from 1-160 amino acids of human GADD45B
属性
| Full name: | growth arrest and DNA damage inducible beta |
| Synonyms: | MYD118; GADD45BETA |
| Swissprot: | O75293 |
| Gene Accession: | BC113466 |
| Gene ID: | 4616 |
| Purity: | >85%, as determined by Coomassie blue stained SDS-PAGE |
| Expression system: | Escherichia coli |
| Tags: | His tag C-Terminus, GST tag N-Terminus |
| Research areas: | Signal Transduction, Epigenetics and Nuclear Signaling, Cancer, Immunology |
| Reconstitution: | Reconstitute with sterile distilled water or deionized water to 1 mg/ml |
| Background: | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008] (The background information is obtained from official databases and does not represent the product information.) |
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