
Order NO. D661077
PDCD1 抗原(多肽片段)


英文名 | PDCD1 Antigen (Peptide fragment) | ||
相关类别 | 抗原 | 储存 | 冷冻(-20℃) |
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
D661077-0001 | 1 MG | 预计30日内发货 |
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产品描述
概述
Synthetic peptide corresponding to a region derived from 270-284 amino acids of human Programmed cell death 1
属性
Full name | Programmed cell death 1 |
Synonyms | PD1, PD-1, CD279, SLEB2, hPD-1, hPD-l |
Swissprot | Q15116 |
Gene Accession | NP_005009 |
Background | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |