英文名 | PD 151746 | ||
级别 | For Signal Pathway Regulation | 相关类别 | 泛素化 |
储存 | 冷冻(-20℃) | 分子量 | 237.25 |
靶点 | Cysteine Protease|Proteasome | ||
编 号 | 包装 | 库存 | 目录价(¥) | 您的价格(¥) | 数 量 |
A423953-0001 | 1 MG | 咨询 |
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A423953-0005 | 5 MG | 咨询 |
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A423953-0010 | 10 MG | 咨询 |
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A423953-0025 | 25 MG | 咨询 |
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A423953-0050 | 50 MG | 咨询 |
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概述
PD151746 is a calpain inhibitor with a 20-fold selectivity for u-calpain (Ki = 0.26 ± 0.03 μM) over m-calpain (Ki = 5.33 ± 0.77 μM). Its IC50 values are 0.26 ± 0.03 μM (Ki for μ-calpain) and 5.33 ± 0.77 μM (Ki for m-calpain) [1]. In vitro, PD151746 targets calpain and reduces oxLDL-induced cytotoxicity [2].
属性
保存温度&条件 | 粉末:-20°C,2年;在溶剂中:-80°C,1年 |
信号通路 | 泛素化|蛋白酶体 |