Order NO. A429205
CAS : [2079938-92-2]
化合物JHU395
| 英文名 | JHU395 | ||
| 级别 | For Signal Pathway Regulation | 相关类别 | 凋亡 |
| 储存 | 冷冻（-20℃） | 分子量 | 447.48 |
| 靶点 | Apoptosis | ||
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| 编 号 | 包装 | 库存 | 目录价（￥） | 您的价格（￥） | 数 量 |
| A429205-0001 | 1 MG | 咨询 |
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| A429205-0005 | 5 MG | 咨询 |
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| A429205-0010 | 10 MG | 咨询 |
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| A429205-0025 | 25 MG | 咨询 |
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| A429205-0050 | 50 MG | 咨询 |
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| A429205-0100 | 100 MG | 咨询 |
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| A429205-0500 | 500 MG | 咨询 |
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产品描述
概述
JHU395 is an orally-bioavailable prodrug of a lipophilic glutamine antagonist (GA), 6-diazo-5-oxo-L-norleucine (DON). It demonstrates delivery of DON to malignant peripheral nerve sheath tumor (MPNST) both in vitro and in vivo, resulting in significant antitumor activity in MPNST. Additionally, JHU395 exhibits plasma stability.
属性
| 保存温度&条件 | 粉末：-20°C，3年；在溶剂中：-80°C，1年 |
| 信号通路 | 凋亡 |
安全信息