重组人ASP, None, E.coli,Recombinant Human Autophagy Related 5 Homolog , None, E.coli 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C520422

重组人ASP, None, E.coli

英文名	Recombinant Human Autophagy Related 5 Homolog , None, E.coli
相关类别	其他重组蛋白	储存	冷冻（-20℃）
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产品描述

概述

Recombinant Human Autophagy Related 5 Homolog is produced by our E.coli expression system and the target gene encoding Met1-Asp275 is expressed.

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

Tag	None
种属	Human
表达系统	E.coli
Accession#	Q9H1Y0
Source	E.coli
Formulation_Description	Supplied as a 0.2 μm filtered solution of 20mM Tris, 0.2M NaCl, 1mM DTT, 40%Glycerol, pH 8.0 .
Storage	Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
Purity	Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin	Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background	ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.