重组人CD86, C-6His, Human cells,Recombinant Human CD86 , C-6His, Human cells 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C520434

重组人CD86, C-6His, Human cells

英文名	Recombinant Human CD86 , C-6His, Human cells
相关类别	其他重组蛋白	储存	冷冻（-20℃）
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编号	包装	库存	目录价（￥）	您的价格（￥）	数量
C520434-0010	10 UG	预计10日内发货			暂不支持线上订购
C520434-0050	50 UG	预计10日内发货			暂不支持线上订购

产品描述

概述

Recombinant Human CD86 is produced by our Mammalian expression system and the target gene encoding Ala24-Pro247(Val185Ile) is expressed with a 6His tag at the C-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag	C-6His
种属	Human
表达系统	Human cells
Accession#	P42081
Source	Human Cells
Formulation_Description	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution	Dissolve the lyophilized protein in distilled water.
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin	Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background	The protein is the receptor that involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. It may play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. The protein interacts with MARCH8， human herpesvirus 8 MIR2 protein, adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.It is expressed by activated B-lymphocytes and monocytes and promoted by MARCH8 and results in endocytosis and lysosomal degradation.It contains 1 Ig-like C2-type(immunoglobulin-like) domainand 1 Ig-like V-type (immunoglobulin-like) domain.