Order NO. C520820
产品描述
概述
Recombinant Human Cystatin C is produced by our Mammalian expression system and the target gene encoding Ser27-Ala146 is expressed.
使用说明
This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
属性
Tag |
None
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种属 |
Human
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表达系统 |
Human Cells
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Accession# |
P01034
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Source |
Human Cells
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Formulation_Description |
Lyophilized from a 0.2 μm filtered solution of 10mM PB, 200mM Nacl, pH6.5.
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Storage |
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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Reconstitution |
Dissolve the lyophilized protein in distilled water.
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Purity |
Greater than 95% as determined by reducing SDS-PAGE.
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Endotoxin |
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
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Background |
Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.
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