重组人PSD95, N-6His, E.coli,Recombinant Human Postsynaptic Density Protein 95 , N-6His, E.coli 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C520863

重组人PSD95, N-6His, E.coli

英文名	Recombinant Human Postsynaptic Density Protein 95 , N-6His, E.coli
相关类别	其他重组蛋白	储存	冷冻（-20℃）

编号	包装	库存	目录价（￥）	您的价格（￥）	数量
C520863-0050	50 UG	预计10日内发货

产品描述

概述

Recombinant Human Postsynaptic Density Protein 95 is produced by our E.coli expression system and the target gene encoding Met1-Leu724 is expressed with a 6His tag at the N-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag	N-6His
种属	Human
表达系统	E.coli
Accession#	P78352
Source	E.coli
Formulation_Description	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution	Dissolve the lyophilized protein in distilled water.
Purity	Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin	Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background	Disks large homolog 4(DLG4) is a cell membrane protein and it is a member of the membrane-associated guanylate kinase (MAGUK) family. The protein contains 1 guanylate kinase-like domain，3 PDZ (DHR) domains and 1 SH3 domain. With PSD-93 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. DLG4 is the best studied member of the MAGUK-family of PDZ domain-containing proteins. Like all MAGUK-family proteins, its basic structure includes three PDZ domains, an SH3 domain, and a guanylate kinase-like domain (GK) connected by disordered linker regions. It is almost exclusively located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins. Its direct and indirect binding partners include neuroligin, NMDA receptors, AMPA receptors, and potassium channels.