Order NO. C521651
产品描述
概述
Recombinant Human Protein Disulfide-Isomerase-Like Protein of the Testis is produced by our Mammalian expression system and the target gene encoding Ser21-Leu584 is expressed with a 6His tag at the C-terminus.
使用说明
This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
属性
Tag |
C-6His
|
种属 |
Human
|
表达系统 |
Human cells
|
Accession# |
Q8N807
|
Source |
Human Cells
|
Formulation_Description |
Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 8.0.
|
Storage |
Store at < -20°C, stable for 6 months after receipt.Please minimize freeze-thaw cycles.
|
Purity |
Greater than 90% as determined by reducing SDS-PAGE.
|
Endotoxin |
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
|
Background |
Protein Disulfide-Isomerase-Like Protein of the Testis (PDILT) is a protein that belongs to the protein disulfide isomerase family. Human PDILT is synthesized as a 584 amino acid precursor that contains an 20 amino acid signal sequence and a 564 amino acid mature chain. PDILT contains 1 thioredoxin domain lacks the conserved redox-active Cys at position 417 which is replaced by a Ser residue, suggesting that it lacks thioredoxin activity. PDILT is an enzyme in the endoplasmic reticulum in eukaryotes. It is not a disulfide-linked homodimer. The PDILT protein can interacts with ERO1L and CLGN. PDILT probable redox-inactive chaperone involved in spermatogenesis.
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