重组人TGF-beta receptor type-2, C-Fc, Human cells,Recombinant Human Transforming Growth Factor-beta Receptor Type II , C-Fc, Human cells 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C521998

重组人TGF-beta receptor type-2, C-Fc, Human cells

英文名	Recombinant Human Transforming Growth Factor-beta Receptor Type II , C-Fc, Human cells
相关类别	其他重组蛋白	储存	冷冻（-20℃）
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
C521998-0010	10 UG	预计14日内发货	待询价	待询价	－ +
C521998-0050	50 UG	预计10日内发货	待询价	待询价	－ +

产品描述

概述

Recombinant Human Transforming Growth Factor-beta Receptor Type II is produced by our Mammalian expression system and the target gene encoding Thr23-Asp159 is expressed with a Fc tag at the C-terminus.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Tag	C-Fc
种属	Human
表达系统	Human cells
Accession#	P37173
Source	Human Cells
Formulation_Description	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Storage	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Reconstitution	Dissolve the lyophilized protein in distilled water.
Purity	Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin	Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test.
Background	TGFBR2 is a single-pass type I membrane protein and contains one protein kinase domain. TGFBR2 exsits as a heterodimeric complex with another receptor protein and binds TGF-beta. Signals triggered through the TGF-beta receptor complex prompt various responses by the cell. One such response is to inhibit cell growth and division. Based on this action, the TGF-beta receptor type 2 is sometimes called a tumor suppressor. Defects in TGFBR2 have been associated with Marfan syndrome, Loeys-Deitz aortic aneurysm syndrome, Osler-Weber-Rendu syndrome and the development of various types of tumors.