重组猴S100B,Recombinant Rhesus Macaque S100 Calcium 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C600227

重组猴S100B

英文名	Recombinant Rhesus Macaque S100 Calcium
相关类别	细胞因子	储存	冷冻（-20℃）
分子量	Approximately 10.6 kDa, a single non-glycosylated polypeptide chain containing 91 amino acids
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
C600227-0010	10 UG	咨询	1461	1461	－ +

产品描述

概述

S100B belongs to the S100 family, which containing 2 EF-hand calcium-binding motifs. In humans, S100B protein is encoded by the S100P gene located at 4q16, but genes that encode other numbers of s100 family proteins are almost located at 1q21 as a cluster. S100B is glial-specific and is expressed primarily by astrocytes. Not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS it acts as a neurotrophic factor and neuronal survival protein.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 97 % by SDS-PAGE and HPLC analyses.
Source	Escherichia coli.
Biological Activity	Data Not Available.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS, pH 7.4.
Endotoxin	Less than 1 EU/μg of rRhS100B as determined by LAL method.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence	SELEKAMVAL IDVFHQYSGR EGDKHKLKKS ELKELINNEL SHFLEEIKEQ EVVDKVMETL DSDGDGECDF QEFMAFVAMV TTACHEFFEH E