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Order NO. C600294
重组大鼠MDC/CCL22
英文名 Recombinant Rat Macrophage-Derived Chemokine/CCL22
别名 MDC/CCL22, Rat
相关类别 趋化因子 储存 冷冻(-20℃)
分子量 Approximately 7.9 kDa, a single, non-glycosylated polypeptide chain containing 68 amino acids.    
编 号 包装 库存 目录价(¥) 您的价格(¥) 数 量
C600294-0005 5 UG 预计20日内发货
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产品描述

概述

CCL22 is a protein encoded by the CCL22 gene. It is highly expressed in macrophage, monocyte-derived dendritic cell and thymus, additionally, also detected in the tissues of thymus, lymph node and appendix. CCL22 can bind to CCR4, and is a chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells, but not for neutrophils, eosinophils, and resting T-lymphocytes. After secreted from monocyte-derived dendritic cells, the protein can be proteolytic cleaved into three forms: MDC (3-69), MDC (5-69), MDC (7-69).

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
Purity > 96 % by SDS-PAGE and HPLC analyses.
Source Escherichia coli.
Biological Activity Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 10-100 ng/ml.
Formulation Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH7.4.
Endotoxin Less than 1 EU/μg of rRtMDC/CCL22 as determined by LAL method.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence GPYGANVEDS ICCQDYIRHP LPPRFVKEFY WTSKSCRKPG VVLITIKNRD ICADPRMLWV KKILHKLA
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