重组人Rb，137a.a.,Recombinant Human Retinoblastoma-Associated Protein Fragment, 137a.a. with His-tag 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C600309

重组人Rb，137a.a.

英文名	Recombinant Human Retinoblastoma-Associated Protein Fragment, 137a.a. with His-tag
别名	Rb, 137a.a., Human
相关类别	其他重组蛋白	储存	冷冻（-20℃）
分子量	Approximately 16.5 kDa, a single non-glycosylated polypeptide chain containing 146 amino acids.
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
C600309-0010	10 UG	预计5日内发货	待询价	待询价

产品描述

概述

Rb encoded by the RB1 gene in humans, is expressed by retina and belongs to the etinoblastoma-associated protein family. The hole protein consists of 928 a.a. and the rHuRb fragment occupies sequence of 792-929 a.a.. Rb is a key regulator of entry into cell division that acts as a tumor suppressor. It has many functions, for example, promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C, and acts as a transcription repressor of E2F1 target genes and so on. The rHuRb is the region that rich of modified residue like phosphothreonine and N6-acetyllysine.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 95 % by SDS-PAGE and HPLC analyses.
Source	Escherichia coli.
Formulation	Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
Endotoxin	Less than 1 EU/μg of rHuRb137, His as determined by LAL method.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence	MASFPSSPLR IPGGNIYISP LKSPYKISEG LPTPTKMTPR SRILVSIGES FGTSEKFQKI NQMVCNSDRV LKRSAEGSNP PKPLKKLRFD IEGSDEADGS KHLPGESKFQ QKLAEMTSTR TRMQKQKMND SMDTSNKEEK HHHHHH