重组小鼠Bcl-xL,Recombinant Murine B-cell lymphoma-extra 生命科学产品与技术服务-生工生物工程(上海)股份有限公司

Order NO. C600428

重组小鼠Bcl-xL

英文名	Recombinant Murine B-cell lymphoma-extra
相关类别	其他重组蛋白	储存	冷冻（-20℃）
分子量	Approximately 23.7 kDa, a single non-glycosylated polypeptide chain containing 211 amino acids.
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编号	规格	库存	目录价（￥）	您的价格（￥）	数量
C600428-0010	10 UG	咨询	待询价	待询价

产品描述

概述

Bcl-xL is a transmembrane protein located in the mitochondrial membranes of cells that are long-lived and postmitotic, such as adult brain cells. It plays a role in the signal transduction pathway of the FAS-Ligand. Bcl-xL is an anti-apoptotic protein which is a member of the Bcl-2 family which are able to form heterodimers, and this is an significant event in the regulation of apoptosis. It is involved in the survival of cancer cells. Bcl-xL is the leading monitor of apoptosis/active cell suicide. It has cell death repressor activity and therefore acts as a survival protein. The murine Bcl-xL shares 97 % and 99 % a.a. sequence identity with human and rat Bcl-xL, respectively.

使用说明

This material is offered by Sangon Biotech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.

属性

Physical Appearance	Sterile Filtered White lyophilized (freeze-dried) powder.
Purity	> 97 % by SDS-PAGE and HPLC analyses.
Source	Escherichia coli.
Biological Activity	Test in Process.
Formulation	Lyophilized from a 0.2 μm filtered concentrated solution in 2 × PBS, pH 7.4, 5 % Trehalose.
Endotoxin	Less than 0.1 EU/μg of rMuBcl-xL as determined by LAL method.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
AA Sequence	SQSNRELVVD FLSYKLSQKG YSWSQFSDVE ENRTEAPEET EAERETPSAI NGNPSWHLAD SPAVNGATGH SSSLDAREVI PMAAVKQALR EAGDEFELRY RRAFSDLTSQ LHITPGTAYQ SFEQVVNELF RDGVNWGRIV AFFSFGGALC VESVDKEMQV LVSRIASWMA TYLNDHLEPW IQENGGWDTF VDLYGNNAAA ESRKGQERFN R